I installed PureOS 10 byzantium (from USB-Install-Drive made with pureos-10~devel-gnome-live-20220102_amd64.iso via Etcher) on my Librem 15v3.
After the installation was finished and first update & upgrade runs were done, I noticed that the CPU Fan starts to run on maximum level after the Librem had been on "suspend to RAM", when a USB-Drive is plugged in. No difference if the Laptop was send to suspend with "Fn + Esc" or by closing the lid or after energy saving activated suspend.
I also tried different drives (HDD, SDD, USB-Sticks). The issue could be reproduced with all of them and disappeard after unplugging the drive.