I have been using separate / and /home partitions for a few years now, and I find that it provides a nice separation between system data and user data, which allows easy, (nearly) worry-free OS reinstalls, particularly as more package systems (Flatpak, pip, others) allow user-installation via some flag like --user.

The question becomes one of default partition sizes. I'd vote for a 50G root parition, with the rest of the disk going to the user (and perhaps a bit of swap).